The methodology of input-output balance for industrial policy plays a key role. First of all, the balance method allows you to manage the structural proportions of the national economy, maintaining optimal proportions between the producing industries and service industries. Keeping producing industries in the optimal proportion to service industries in the GDP structure is the basis of national economic security preservation. Failure to manage the national economy based on the methodology of intersectoral balance in the 90s of 20th century has led to structure degradation of the Russian national economy and increasing its dependence on external factors. At the same time in the Western countries the intersectoral balancemethodology received a «second birth» and is currently undergoing a renaissance. New global threats force one to rethink the practical importance of the balance method in the national economy and dictate the feasibilityof the return to the experience of scientific management of the national economy of the Soviet period on adifferent quality level.